Post-polio syndrome is associated with which symptoms?

• A. Acute fever and rash
• B. Muscle weakness, fatigue, and pain years after initial infection
• C. Shortness of breath only
• D. Severe dehydration

Answer: (B)

Post-polio syndrome arises many years after the original poliomyelitis infection and represents a late-onset decline in function of muscles that were previously affected. The most characteristic signs are new or worsening muscle weakness, along with fatigue and muscle or joint pain, occurring long after the initial illness. That combination directly matches what this question asks about.

Acute fever and rash point to a new or different infection rather than a delayed neuromuscular decline. Shortness of breath can occur if breathing muscles are involved, but it’s not the defining pattern by itself. Severe dehydration is not a feature of post-polio syndrome.