VAPP stands for what?

• A. Vaccine-associated paralytic poliomyelitis.
• B. Viral-associated poliomyelitis.
• C. Vaccine-associated post-polio.
• D. Varicella-associated poliomyelitis.

Answer: (A)

Vaccine-associated paralytic poliomyelitis is the recognized term. This describes a rare adverse event after vaccination with the oral polio vaccine, which contains live, attenuated poliovirus. In some individuals the weakened vaccine virus can revert toward neurovirulence and cause paralysis, producing a clinical picture indistinguishable from wild poliomyelitis but linked to the vaccine strain. This condition is distinct from paralytic poliomyelitis caused by wild-type virus or from post-polio syndrome, which occurs in people who had polio in the past. The other options aren’t standard terms for this condition.