Which samples can shed OPV vaccine strains be detected in?

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Study for the Poliovirus and Poliomyelitis Test. Prepare with engaging flashcards and detailed multiple-choice questions, each with hints and explanations. Ace your exam with confidence!

Multiple Choice

Which samples can shed OPV vaccine strains be detected in?

Explanation:
The key idea is that the live attenuated poliovirus from the oral vaccine replicates in the gut and is shed in feces. Because of this, the most reliable way to detect OPV vaccine strains is in stool and in environmental samples from sewage, where shedding into wastewater can be picked up and monitored for circulation in a population. Other sample types aren’t the standard for detecting OPV shedding. Blood may show only brief or no viremia after vaccination, and saliva, urine, tears, or bone marrow aren’t practical or reliable matrices for monitoring shed OPV strains.

The key idea is that the live attenuated poliovirus from the oral vaccine replicates in the gut and is shed in feces. Because of this, the most reliable way to detect OPV vaccine strains is in stool and in environmental samples from sewage, where shedding into wastewater can be picked up and monitored for circulation in a population.

Other sample types aren’t the standard for detecting OPV shedding. Blood may show only brief or no viremia after vaccination, and saliva, urine, tears, or bone marrow aren’t practical or reliable matrices for monitoring shed OPV strains.

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