Which structural proteins form the poliovirus capsid?

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Multiple Choice

Which structural proteins form the poliovirus capsid?

Explanation:
Poliovirus capsids are built from four structural proteins: VP1, VP2, VP3, and VP4. These proteins come from the viral P1 region and are arranged to form the icosahedral shell that encloses the RNA genome. During maturation, the precursor VP0 is cleaved into VP2 and VP4, so the mature virion contains VP1, VP2, VP3, and VP4. This four-protein composition is essential for a stable, properly assembled capsid with the correct surface features and internal stabilization. If a sequence included only three of these proteins or replaced one with a precursor like VP0, it wouldn’t form the complete mature capsid architecture. Hence, the capsid is formed by VP1, VP2, VP3, and VP4.

Poliovirus capsids are built from four structural proteins: VP1, VP2, VP3, and VP4. These proteins come from the viral P1 region and are arranged to form the icosahedral shell that encloses the RNA genome. During maturation, the precursor VP0 is cleaved into VP2 and VP4, so the mature virion contains VP1, VP2, VP3, and VP4. This four-protein composition is essential for a stable, properly assembled capsid with the correct surface features and internal stabilization.

If a sequence included only three of these proteins or replaced one with a precursor like VP0, it wouldn’t form the complete mature capsid architecture. Hence, the capsid is formed by VP1, VP2, VP3, and VP4.

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